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New non-invasive treatment for Trigeminal Schwannoma-CyberKnife

March 23rd, 2009 · 2 Comments

The other night while doing my nightly research I came across the most wonderful article.  It was just published in February 2009. Dr. John Adler, the best neurosurgeon in the world (the surgeon who has been taking care of Travis) has reported that 13 consecutive patients with Trigeminal Schwannomas were treated with CyberKnife between 2003-2007.  The CyberKnife treatment resulted in the tumor control rate of 100%.

You can’t ask for anymore than that.  I also got excited thinking that Travis was one of the patients included in the study.  We have not confirmed that Travis was one of the individuals discussed in the article but he will be asking his surgeon tomorrow on his visit.

I will paste the article below and a link to where I found it.

http://journals.lww.com/neurosurgery/Abstract/2009/02001/Cyberknife_Radiosurgery_for_Trigeminal_Schwannomas.4.aspx

Cyberknife Radiosurgery for Trigeminal Schwannomas
Sakamoto, Gordon T.; Borchers, D. John III; Xiao, Furen; Yang, Hee-Jin; Chang, Steven D.; Adler, John R. Jr.
Abstract
OBJECTIVE: Trigeminal schwannomas (TS) are benign tumors that are managed by surgical resection and/or stereotactic radiosurgery. Most radiosurgical series report results using the gamma knife. The CyberKnife (Accuray, Inc., Sunnyvale, CA) is a frameless, robotic stereotactic radiosurgical system. In this series, we report our experience using the CyberKnife in the treatment of TS.
METHODS: We retrospectively reviewed the medical records and diagnostic imaging in 13 consecutive patients with TS who were treated with the CyberKnife from 2003 to 2007. Seven patients had a previous surgical resection. The mean tumor volume was 6.3 mL (range, 0.39-19.98 mL), and the mean marginal dose was 18.5 Gy. Six of the tumors were treated in a single session. The mean clinical follow-up period was 21.8 months (range, 7-53 months).
RESULTS: In this series, the tumor control rate was 100%. The average reduction in tumor volume was 45% (range, 14-98%). A modest improvement in facial pain was noted in 4 of the 6 patients who presented with this symptom. One patient had improvement in facial numbness, and another had improvement in pretreatment headaches. One patient developed jaw weakness and facial dysesthesia, and another patient developed asymptomatic radiation necrosis.
CONCLUSION: Although the length of follow-up is limited, we report our initial experience with CyberKnife treatment of TS. Our results demonstrate tumor control rates and clinical outcomes that parallel those of previous reports using gamma knife radiosurgery; however, long-term follow-up studies are needed.

Tags: Brain Tumor · CyberKnife · Cyberknife radiation · Dr. Adler · radiation · Radiosurgery · surgery · Trigeminal schwannoma · tumor